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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MATK All Species: 0
Human Site: S458 Identified Species: 0
UniProt: P42679 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42679 NP_002369.2 507 56469 S458 G P V H V L M S S C W E A E P
Chimpanzee Pan troglodytes XP_512276 328 36052 P290 E A E P A R R P P F R K L A E
Rhesus Macaque Macaca mulatta XP_001101430 450 50702 P412 M D A P D G C P P A V Y E V M
Dog Lupus familis XP_854815 843 91685 G697 G P I H A L M G S C W E A E P
Cat Felis silvestris
Mouse Mus musculus P41242 505 56038 G456 G S V H T L M G S C W E A E P
Rat Rattus norvegicus P41243 467 51878 P429 E A E P S R R P P F R K I V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P41239 450 50733 P412 M D P P D G C P A I V Y E V M
Frog Xenopus laevis P13116 532 59718 M494 P E S L H D L M F Q C W R K D
Zebra Danio Brachydanio rerio XP_695792 445 50295 E407 Y R M D P P D E C P A D V Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_731611 1052 113728 P1012 V G Y K M E A P E G C P P E I
Honey Bee Apis mellifera XP_393399 493 55500 H454 E P P D G C P H E V Y D I M R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795344 763 85563 P725 K G Y R M E S P E G C P D H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 47.1 56.8 N.A. 87.1 82.2 N.A. N.A. 46.9 34 56 N.A. 24.8 40 N.A. 32.2
Protein Similarity: 100 64.6 64.6 58.8 N.A. 92.3 87.5 N.A. N.A. 65.6 49.2 71.4 N.A. 33.1 57.5 N.A. 42.9
P-Site Identity: 100 0 0 80 N.A. 80 0 N.A. N.A. 0 0 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 6.6 0 86.6 N.A. 80 6.6 N.A. N.A. 6.6 13.3 13.3 N.A. 13.3 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 17 0 9 0 9 9 9 0 25 9 0 % A
% Cys: 0 0 0 0 0 9 17 0 9 25 25 0 0 0 0 % C
% Asp: 0 17 0 17 17 9 9 0 0 0 0 17 9 0 9 % D
% Glu: 25 9 17 0 0 17 0 9 25 0 0 25 17 34 17 % E
% Phe: 0 0 0 0 0 0 0 0 9 17 0 0 0 0 0 % F
% Gly: 25 17 0 0 9 17 0 17 0 17 0 0 0 0 0 % G
% His: 0 0 0 25 9 0 0 9 0 0 0 0 0 9 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 9 0 0 17 0 9 % I
% Lys: 9 0 0 9 0 0 0 0 0 0 0 17 0 9 0 % K
% Leu: 0 0 0 9 0 25 9 0 0 0 0 0 9 0 0 % L
% Met: 17 0 9 0 17 0 25 9 0 0 0 0 0 9 17 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 25 17 34 9 9 9 50 25 9 0 17 9 0 25 % P
% Gln: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Q
% Arg: 0 9 0 9 0 17 17 0 0 0 17 0 9 0 9 % R
% Ser: 0 9 9 0 9 0 9 9 25 0 0 0 0 0 9 % S
% Thr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % T
% Val: 9 0 17 0 9 0 0 0 0 9 17 0 9 25 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 25 9 0 0 0 % W
% Tyr: 9 0 17 0 0 0 0 0 0 0 9 17 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _